Wednesday, 21 February 2018 CAT (UTC+2)
Pamplemousses 1 - 0 Bidvest Wits
 [Agg: 1-2] 
   
BE FORWARD Wanderers 1 - 2 Vita Club
 [Agg: 1-6] Peter Wadabwa - 20' J. Makusu, 65' J. Baoyi 
   
KCCA 1 - 0 CNaPS Sport
 [Agg: 2-2] 63' P. Macureezi 
   
ZESCO United 7 - 0 JKU Zanzibar
 [Agg: 7-0] 3', 42', 57', 61' A. Zikiru, 42' L. Kambole, W. Kalengo, L. Banda 
   
UD Songo 2 - 0 Ngaya Club
 Agg: 3-1 
   
Platinum 1 - 2 Primeiro Agosto
 Agg: 1-5 
   
LLB Academic 0 - 1 Rayon Sports
 Agg: 1-2 
   
Saint Louis Suns United 1 - 1 Young Africans
 [Agg: 1-2] 90+3' B. Esther - 45' I. Migomba 
   
Mbabane Swallows 1 - 3 Bantu
 [Agg: 5-5] 
   
Benfica Bissau 0 - 0 Difaa Hassani
 [Agg: 0-10] 
   
CF Mounana 2 - 0 RC Kadiogo
 [Agg: 2-1] 29' A. Nono, 55' A. Atchabao 
   
Eding Sport 0 - 1 Plateau United
 [Agg: 0-4] 52' R. Ayagwa 
   
Aduana Stars 2 - 0 Al Tahaddy
 [Agg: 2-1] 53' E. Opoku, 74' D. Sasraku 
   
MFM 1 - 0 Real Bamako
 [Agg: 2-1] 
   
Togo Port 2 - 1 AC Leopards
 [Agg: 3-3] [Pen. 4-3] 
   
Leones Vegetarianos 1 - 1 Gor Mahia
 [Agg: 1-3] 
   
Esperance 5 - 0 Concorde
 [Agg: 6-1] 6', 54' [P] A. Badri, 72' [P] M. Sghaier, 82' H. Rabii, 84' F. Coulibaly 
   
ASEC Mimosas 3 - 2 Buffalo Borgou
 [Agg: 4-3] 29' K. Agbegniadan, 51' G. Badie, 75' A. Toure - 49' A. Bawa, 66' J. Agognon 
   
Horoya 0 - 0 FAN Niamey
 [Agg: 3-1] 
   
Misr Lel Makkasa 0 - 0 Generation Foot
 [Agg: 0-2] 
   
Al Merreikh 2 - 1 Township Rollers
 [Agg: 2-4] 19' S. Fofanah, 84' A. Ahmed - 2' J. Mogorosi 
   
MC Alger 9 - 0 Otoho
 [Agg: 9-2] 5' [P] W. Derrardja, 23', 61', 66', 80', H. Nekkache, 33' M. Souibaah, 70' A. Hachoud, 76' A. Balegh 
   
Saturday, 24 February 2018 CAT (UTC+2)
Armed Forces vs Zanaco
6:30 pm Independence Stadium
   

85' BF Wanderers 1-2 Vita Club
([Agg: 1-6] Peter Wadabwa - 20' J. Makusu, 65' J. Baoyi)

2 days ago

HT: BF Wanderers 1-2 Vita Club
([Agg: 1-6])

3 days ago

HT: BF Wanderers 0-1 Vita Club
([Agg: 0-5]) 20' ?

3 days ago

HT: BF Wanderers 0-1 Vita Club
([Agg: 0-5])

3 days ago

HT: Williamsville 0-0 Stade Malien (Agg: 1-1)

3 days ago

HT: ORB (0)0-0(6) ESS

3 days ago

HT: ORB 0-0 ESS

3 days ago

81' ES Setif 5-0 OR Bangui

12 days ago

85' Real Bamako 1-1 MFM
(17' M. Giscard - 15' N. Akinyemi)

12 days ago

HT: Real Bamako 1-1 MFM
(? - 15' N. Akinyemi)

12 days ago