Tuesday, 20 February 2018 CAT (UTC+2)
Masters Security 0 - 0 Petro Atletico 2:30 pm
Agg: 0-5  Bingu National Stadium 
   
Hafia 1 - 1 Energie 6:30 pm
[Agg: 1-2] 90' S. Guera  Stade 28 Septembre 
   
Cape Town City 1 - 0 Young Buffaloes 7:30 pm
[Agg: 2-0] 57' A. Ralani  Athlone Stadium 
   
Wednesday, 21 February 2018 CAT (UTC+2)
Jwaneng Galaxy vs Costa Do Sol 5:00 pm
  Lobatse Stadium